{"id":3961,"date":"2024-12-04T16:52:04","date_gmt":"2024-12-04T16:52:04","guid":{"rendered":"https:\/\/www.finden.co.uk\/?p=3961"},"modified":"2024-12-04T16:55:35","modified_gmt":"2024-12-04T16:55:35","slug":"spatial-and-temporal-visualization-of-polymorphic-transformations-in-pharmaceutical-tablets","status":"publish","type":"post","link":"https:\/\/www.finden.co.uk\/zh\/news\/spatial-and-temporal-visualization-of-polymorphic-transformations-in-pharmaceutical-tablets\/","title":{"rendered":"Spatial and Temporal Visualization of Polymorphic Transformations in Pharmaceutical Tablets"},"content":{"rendered":"

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Our Senior Scientist Stephen Price has been working with Julia Gasol Cardona<\/a>, Iain Oswald<\/a> (University of Strathclyde), Daniel Markl<\/a> (CMAC), Andy Maloney<\/a> (CCDC – The Cambridge Crystallographic Data Centre), and teams at DESY<\/a>, ELDICO Scientific AG<\/a> and ESRF – The European Synchrotron<\/a> on a project where X-ray Diffraction Computed Tomography (XRD-CT) has been used to reveal pressure-induced phase transformations in pharmaceutical tablets of glycolide as a function of compaction pressure. This novel application of the XRD-CT methodology enables non-destructive molecular level insight and is a step change in the way we are able to view formulated products. In the broader context of pharmaceutical research, the application of this methodology to pharmaceutically relevant systems will enable a deeper understanding of the effect of tableting pressure on the formulation in pharmaceutical products. Read the article at https:\/\/doi.org\/10.1002\/anie.202412976<\/a><\/p>","protected":false},"excerpt":{"rendered":"

Our Senior Scientist Stephen Price has been working with Julia Gasol Cardona, Iain Oswald (University of Strathclyde), Daniel Markl (CMAC), Andy Maloney (CCDC – The Cambridge Crystallographic Data Centre), and teams at DESY, ELDICO Scientific AG and ESRF – The European Synchrotron on a project where X-ray Diffraction Computed Tomography (XRD-CT) has been used to […]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[15],"tags":[],"class_list":["post-3961","post","type-post","status-publish","format-standard","hentry","category-news"],"_links":{"self":[{"href":"https:\/\/www.finden.co.uk\/zh\/wp-json\/wp\/v2\/posts\/3961","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.finden.co.uk\/zh\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.finden.co.uk\/zh\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.finden.co.uk\/zh\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.finden.co.uk\/zh\/wp-json\/wp\/v2\/comments?post=3961"}],"version-history":[{"count":4,"href":"https:\/\/www.finden.co.uk\/zh\/wp-json\/wp\/v2\/posts\/3961\/revisions"}],"predecessor-version":[{"id":3966,"href":"https:\/\/www.finden.co.uk\/zh\/wp-json\/wp\/v2\/posts\/3961\/revisions\/3966"}],"wp:attachment":[{"href":"https:\/\/www.finden.co.uk\/zh\/wp-json\/wp\/v2\/media?parent=3961"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.finden.co.uk\/zh\/wp-json\/wp\/v2\/categories?post=3961"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.finden.co.uk\/zh\/wp-json\/wp\/v2\/tags?post=3961"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}